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- etymologie
Wat (wie) is RCC1 - definitie
RCC1
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
RCC1 (gene)
Regulator of chromosome condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein.
HERC2
![The cytochrome-b5-like domain of HERC2, captured with NMR spectroscopy [http://www.rcsb.org/structure/2KEO (2KEO)]](https://commons.wikimedia.org/wiki/Special:FilePath/2KEO cytochrome-b5-like domain.jpg?width=200 "The cytochrome-b5-like domain of HERC2, captured with NMR spectroscopy [http://www.rcsb.org/structure/2KEO (2KEO)]")
![The third RLD domain of HERC2, captured at 1.8 Å by X-ray diffraction [http://www.rcsb.org/structure/3KCI (3KCI)]](https://commons.wikimedia.org/wiki/Special:FilePath/3KCI The third RLD domain of HERC2.jpg?width=200 "The third RLD domain of HERC2, captured at 1.8 Å by X-ray diffraction [http://www.rcsb.org/structure/3KCI (3KCI)]")
![The first RLD domain of HERC2, captured at 2.6 Å by X-ray diffraction [http://www.rcsb.org/structure/4L1M (4L1M)]](https://commons.wikimedia.org/wiki/Special:FilePath/4L1M Structure of the first RCC1-like domain of HERC2.jpg?width=200 "The first RLD domain of HERC2, captured at 2.6 Å by X-ray diffraction [http://www.rcsb.org/structure/4L1M (4L1M)]")
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
HERC2 (gene); E3 ubiquitin ligase HERC2
HERC2 is a giant E3 ubiquitin protein ligase, implicated in DNA repair regulation, pigmentation and neurological disorders. It is encoded by a gene of the same name belonging to the HERC family, which typically encodes large protein products with C-terminal HECT domains and one or more RCC1-like (RLD) domains.
